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The end of The Big Bang Theory (Thursdays at 8 p.m. ET on CTV) is almost here and with the series finale set to air with a one-hour special on Thursday, May 16, we’re preparing by getting our tissues lined up for what we know is going to be a tear-jerker of an episode. The cast has been teasing fans about the final season, even posting their own crying shots from the table read of the final episode and sharing their favourite moments from the past 12 seasons. Start hydrating now, people.

The Big Bang Theory has made us laugh and has made us smarter (some of the science must have rubbed off on us, right?) over the past 12 seasons, but it’s also made us emotional. For a show that began as a series that focused on four socially awkward scientists and their hot neighbour, it quickly evolved into a comedy that has given fans some beautiful and heartbreaking moments over the past decade. The ultimate bazinga.

Here are 10 times The Big Bang Theory broke us.

The one-hour series finale of The Big Bang Theory airs Thursday, May 16 at 8 p.m. on CTV.